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Chemical and Biomolecular Engineering

National Science Foundation funds collaborative effort to reimagine creation of chemicals and fuels

David Flaherty
David Flaherty of the Department of Chemical and Biomolecular Engineering

A $2 million grant from the National Science Foundation will help a team of scientists at the University of Illinois develop ways to use renewable energy to remediate carbon dioxide emissions and generate chemical building blocks and liquid fuels. 

The main idea of their proposal is to reimagine the manufacturing of chemicals and fuels as society shifts from using petroleum for these processes to renewable sources such as biomass and carbon dioxide. David Flaherty, professor of chemical and biomolecular engineering and Dow Chemical Faculty Scholar, said he and his colleagues have been laying the intellectual groundwork for this proposal over the past several years.

The team is comprised of five faculty members at the University of Illinois including Flaherty, Andrew Gewirth (chemistry), Paul Kenis (chemical and biomolecular engineering), Joaquín Rodríguez-López (chemistry), and Ashlynn Stillwell (civil and environmental engineering).

The team’s proposal was selected among hundreds of others in a rigorous review process for the grant through National Science Foundation’s Emerging Frontiers in Research and Innovation Research Projects program. Their concept uses renewable energy that comes off the grid from solar or wind power to drive an electrochemical reactor that performs two useful reactions simultaneously.

First, they use one side of the reactor to reduce carbon dioxide to form molecules currently used to make durable goods such as plastics. This will reduce domestic greenhouse gas emissions. However, reducing carbon dioxide requires a large amount of energy, because these reactions are thermodynamically unfavorable, Flaherty said. The challenge here is turning a stable molecule such as carbon dioxide into a much less stable molecule, he said. 

“Another way to think about this is that we are trying to reverse the combustion process that is used to generate energy to move cars or produce electricity in power plants,” Flaherty said.

Second, the other side of the reactor partially oxidizes (or burns) renewable and abundant materials that are locally available. The energy captured from this process helps drive the reduction of carbon dioxide while the oxidation reaction produces useful chemicals. 

“We have to change our approach for making building block chemicals,” Flaherty said. “How do we manufacture chemicals and create fuels and energy that will support all the things we enjoy doing but doing it in a distributed manner that aligns with the location of emerging resources? We need to move away from these hundred-acre petroleum refineries and find solutions that work at smaller scales.”

Paul Kenis
Paul Kenis of the Department of Chemical and Biomolecular Engineering

Kenis, the Elio E.Tarika Endowed Chair in Chemical Engineering, found a way to reduce carbon dioxide that would decrease the amount of renewable energy necessary for the process by up to 50 percent. He found that by coupling the carbon dioxide reduction with a more favorable type of chemistry on the other side of the reactor, the amount of energy necessary will greatly decrease.

“Electrolysis is seen as an option for industry to change over from the present plants to electrolysis processes,” Kenis said.

He added that, as part of the Paris Accord, the chemical industry is in an energy transition from 2020 to 2050 in which the dependency on fossil fuels and the associated carbon dioxide production must be decreased.

This is a win-win-win scenario, Flaherty said. If successful, they will efficiently reduce greenhouse gas emissions, produce renewable chemicals and fuels, and create new job opportunities for operators and engineers in an emerging distributive chemical manufacturing economy.

“We are going to learn so much from each other along the way,” Flaherty said. “We all have our own perspectives, our own expertise, and this is an awesome opportunity for us to tackle a critical challenge. In addition, this will be an excellent way for us to teach students a diverse set of skills they need to solve important societal problems.”

News Source

Samantha Boyle



Congratulations to Chemical and Biomolecular Engineering PhD students who have been selected to receive fellowships from the National Science Foundation Graduate Research Fellowship Program. They include Paola Baldaguez Medina, Vasiliki “Aliki” Kolliopoulos, and Chris Torres.

The NSF program recognizes and supports individuals early in their graduate training in science, technology, engineering, and mathematics fields. The aim is to help ensure the vitality and diversity of the scientific and engineering workforce in the U.S. The program provides three years of support for students who have demonstrated their potential for significant research achievements in STEM or STEM education.

ChBE PhD students who were selected for 2020 National Science Founation Graduate Research Program
NSF fellowship recipients (from left) Paola Baldaguez Medina, Vasiliki “Aliki” Kolliopoulos, and Chris Torres

Baldaguez Medina completed her undergraduate education at the University of Puerto Rico at Mayagüez in 2019. While there, she conducted research in separation processes with Professor Hernández-Maldonado and spectroscopy with Professor Hernández-Rivera. She also had internships at the University of Minnesota through the NSF Research Experiences for Undergraduates (REU) program working on block-copolymers, and at the University of Florida with Professor Rinaldi on rheology studies.

A member of Assistant Professor Xiao Su’s research group at the University of Illinois, her work focuses on developing water remediation techniques via electrochemical mediated systems for the removal of anthropogenic organic contaminants of concern. She uses redox-polymers electrodes for pollutant binding through electrosorption. Developing an electrochemical separation method could impact society in numerous ways by providing energy effective and modular technologies for water purification, Baldaguez Medina said.

Kolliopoulos is a member of Professor Brendan Harley’s lab, which has been developing advances in tissue engineering. Craniofacial bone defects are common in the context of congenital, traumatic, and post-oncologic conditions. Such bone defects are often large in size and heal poorly, motivating regenerative medicine efforts. A particular barrier to regenerative healing is the significant immune and inflammatory response post injury which can inhibit cell recruitment, vascular remodeling, and new tissue biosynthesis. The Harley lab is developing a class of mineralized collagen biomaterials capable of meeting a wide range of design requirements for successful deployment into CMF bone defects, notably the ability to conformally fit complex defect geometries and support stem cell osteogenesis.

Kolliopoulos said she aims to understand the effect of scaffold biophysical properties (microstructure, stiffness, alignment, mineral morphology) on the recruitment and subsequent activation status of macrophages. Her ultimate goal is to demonstrate biomaterials capable of modulating the kinetics of the macrophage response post injury as a means to accelerate implant integration and subsequent bone regeneration. She completed her undergraduate studies at The Ohio State University. In 2018, while working in the Carlos Castro Lab, she received an honorable mention for the NSF GRFP for her work on DNA Origami.

Torres is a member of Associate Professor David Flaherty’s research group. He studies the catalytic role of solid-liquid interfaces and extended solvent networks for liquid-phase oxidation reactions. His research goal is to create design rules for catalysts which reduce the environmental impact of chemical industries. He completed his undergraduate education at the University of New Mexico.

Congratulations to graduate student Daniel Bregante, who was among a select group of Illinois students chosen for a Scholar Award from the ARCS Foundation.

Founded in 1958, the ARCS Foundation was established by and is run entirely by women. Its mission is to boost American leadership and aid advancement in science and technology. To address the country’s need for new scientists and engineers, the foundation provides unrestricted funding to help the country’s brightest graduate and undergraduate students create new knowledge and innovative technologies.

Bregante was among nine students in the state chosen for the award this year by the Illinois chapter of ARCS.

Daniel Bregante

He is a member of Professor David Flaherty’s research group and is in the process of completing his dissertation, “Unraveling Inner- and Outer-Sphere Interactions that Impact Catalysis at the Liquid-Solid Interface.”

Molecular interactions at solid-liquid interfaces can have profound effects on the stability of species that form during catalysis and separations. These interactions become increasingly complex when the solvent and reactive species are confined within nanopores (<1 nm in diameter). Bregante’s research focuses on understanding how the structuring and restructuring of solvent molecules within these nanopores during a chemical reaction leads to changes in catalysis.

His findings have shown that the presence of polar “defects” within the pores of Lewis acid zeolites (i.e., an epoxidation catalyst) leads to increases in rates and selectivities for alkene epoxidation (a multi-billion-dollar industry) by a factor of 100. These results directly contradict conventional wisdom, that states hydrophobic pores leads to the greatest yields. His work has shown, non-intuitively, that the polarity mis-match between hydrophobic surface species and water leads to increases in stability, and thus higher rates. These findings and the conceptual framework developed will provide a broader understanding for interactions between solvents, surfaces, and reactive species, and provide a basis to understand how similar restructuring events may impact critical intermediates within other research fields.

Bregante will be given the award at the ARCS annual reception in Chicago in October. As part of the event, he and fellow scholars will present research posters at the reception.

The Department of Energy has selected 73 scientists from across the nation, including University of Illinois chemical and biomolecular engineering professor David Flaherty, to receive significant funding for research as part of its Early Career Research Program. The effort, now in its tenth year, is designed to bolster the nation’s scientific workforce by providing support to exceptional researchers during the crucial early career years, when many scientists do their most formative work.

David Flaherty

Flaherty’s research project is entitled, “The Role of Cooperative Interactions Among Surfaces, Solvents, and Reactive Intermediates on Catalysis at Liquid-Solid Interfaces.” His lab focuses on the overlapping topics of catalysis, surface science, and materials synthesis.

“Supporting our nation’s most talented and creative researchers in their early career years is crucial to building America’s scientific workforce and sustaining America’s culture of innovation,” said Secretary of Energy Rick Perry in a release announcing the winners. “We congratulate these young researchers on their significant accomplishments to date and look forward to their achievements in the years ahead.”

To be eligible for the award, a researcher must be an untenured, tenure-track assistant or associate professor at a U.S. academic institution or a full-time employee at a Department of Energy national laboratory, who received a Ph.D. within the past 10 years. Research topics are required to fall within one of the Department’s Office of Science’s six major program offices: advanced scientific computing research, basic energy sciences, biological and environmental research, fusion energy sciences, high energy physics, and nuclear physics.

Awardees were selected from a large pool of university- and national laboratory-based applicants. Selection was based on peer review by outside scientific experts. Projects announced today are selections for negotiation of financial award. The final details for each project award are subject to final grant and contract negotiations between the Department of Energy and the awardees.

Under the program, university-based researchers will receive about $150,000 per year to cover summer salary and research expenses. For researchers based at Department of Energy national laboratories, where DOE typically covers full salary and expenses of laboratory employees, grants will be about $500,000 per year to cover year-round salary plus research expenses. The research grants are planned for five years.

A list of the 73 awardees, their institutions, and titles of research projects is available on the Early Career Research Program webpage

Chemical and Biomolecular Engineering Professor David Flaherty has received a new grant from the U.S. Army to develop design rules for solid catalysts for selective oxidations in the liquid-phase.

“To do that, we need to understand how to engineer the electronic structure of atomically dispersed transition metal active sites on oxide supports, which depend on the metals that form the active sites and the manner by which they share electrons with the extended surface of the support,” Flaherty said.

The motivation for the research comes from the wide-spread need for epoxides for the production of advanced materials, industrial solvents, and common consumer goods. The epoxidation of light alkenes (unsaturated hydrocarbons), produced in high volume from traditional fossil reserves and now shale gas, provides reactive building blocks that confer unique properties to polymers and surfactants. As a result, epoxides are produced on a massive scale; the global production and market for ethylene oxide and propylene oxide alone exceeds $45 billion each year.

David Flaherty

“We should be able to control rates and selectivities for epoxidation reactions by electronically modifying the active sites for these reactions through use of different isolated metal atoms or by placing these metal atoms onto surfaces that act like ligands and change their electronic properties,” Flaherty said.

The new grant will fund the building of an apparatus that will allow the lab to characterize the structure of the active site and catalytic intermediates while the reaction is occurring, rather than relying on ex situ characterization methods that are unable to provide the needed information. This problem is well-known, according to Flaherty, as catalysts are dynamic, seemingly animate objects whose appearance and behavior depends strongly on their surroundings. Therefore, in situ characterization is required to learn about the active form of the catalyst.

“The general principles established under this project may enable rational catalyst design towards more reactive and selective catalysts,” said Dawanne Poree, program manager, chemical science, Army Research Office, an element of the U.S. Army Combat Capabilities Development Command’s Army Research Laboratory. “These type of materials could be of great value to the Army, for efficient decomposition of hazardous chemicals for personnel and equipment protection.”

Since 2016, the Flaherty lab has received support from the Army Research Office for its research in this area. The funding for this project, and other projects inspired by the findings, has supported several graduate students and a postdoctoral researcher in the lab and has led to the publication of five articles in highly regarded journals (J. Am. Chem. Soc. ACS Catalysis, J. Catalysis) since 2017.

Flaherty joined the University of Illinois Department of Chemical and Biomolecular Engineering in 2012. He earned his Ph.D. from the University of Texas at Austin in 2010 and his post-doctoral work was completed at the University of California, Berkeley. His lab focuses on the overlapping topics of catalysis, surface science, and materials synthesis.

Congratulations to Dr. David Flaherty, recipient of the Early Career Award from the regional chapter of the American Vacuum Society.

Flaherty, an assistant professor in chemical and biomolecular engineering, received the award at the AVS Prairie Chapter symposium in Chicago earlier this month. He delivered the talk, “Non-Innocent Solvents, Hydrogen Transfer, Oxygen Dissociation on Nanoparticles during the Direct Synthesis of H2O2.”

Daniel Killelea (right), chair of the AVS Prairie Chapter and professor in the Department of Chemistry at Loyola University Chicago, presents the Early Career Award to David Flaherty, assistant professor of chemical and biomolecular engineering at the University of Illinois (left).

The Flaherty Research Group develops new principles needed to design catalytic materials and systems for the sustainable production of consumer products and fuels. Flaherty, who joined the department in 2012, holds a BS from University of California, Berkeley and a PhD from the University of Texas at Austin.

Congratulations Prof. Flaherty!

Congratulations to Alayna Johnson, who has been named a Goldwater Scholar for the 2018-19 academic year!

Alayna is a sophomore majoring in chemistry. As a freshman, she joined the lab of Dr. David Flaherty, assistant professor in the Department of Chemical and Biomolecular Engineering, where her research with team members Daniel Bregante, Ami Patel, and Zeynep Ayla centers on the synthesis of epoxides, which are used to manufacture pharmaceuticals and plastics.

Noting the negative environmental impact of current methods of epoxide synthesis, Johnson elaborated on her team’s goals: “We’re hoping to engineer a catalyst that would allow industries to make epoxides in a new and greener manner. The project is a great combination of materials chemistry, catalysis, and environmental chemistry.”

Goldwater recipient Alayna Johnson. Photo provided.

“Alayna quickly developed skills in kinetic analysis and spectroscopy and has used these tools to show how we can tailor independently the electronic structure, porous structure, and hydrogen bonding interactions of inorganic materials to minimize the environmental impact of these oxidation reactions,” Flaherty said.

Flaherty called Alayna “a talented researcher, a brilliant student, and a truly enjoyable person to work with.”

“In my career, I have rarely seen this strong set of skills in such a young student. Alayna demonstrates her unstoppable drive and motivation in the way she approaches her classwork and research and excels in both,” he said.

Johnson’s experiences in the Flaherty lab also taught her more about herself and her research interests: “I’ve learned that while my interests certainly lie in pure science, an understanding of basic engineering and computational principles is invaluable.”

“The aspect I appreciate most about research is the intellectual freedom that comes with deciding which experiments to run, how to analyze the results, and what to do when they do not match the expected hypothesis. Within research, we get to experience the rare but incredibly rewarding feeling that comes from seeing the results of a well-designed experiment and learning something new about the world,” she said.

Johnson is one of three University of Illinois students to receive the prestigious honor. Read more from the Department of Chemistry.


Chemical and Biomolecular Engineering Professors David Flaherty and Brendan Harley have been named winners of the College of Engineering Dean’s Award for Excellence in Research. The award is given annually to a handful of engineering faculty in recognition of their research. Both will be honored at the college’s faculty awards ceremony on April 23.

Since they joined the department, Professors Harley and Flaherty have emerged as exceptional scientists and mentors, said Paul Kenis, William H. and Janet G. Lycan Professor and Department Head.

“It’s rewarding to see faculty recognized for their dedication to advancing science and leading and training research groups that are doing truly pioneering work. I expect they will continue to push the boundaries of their fields—Harley in biomaterials and Flaherty in heterogeneous catalysis,” Kenis said.

Flaherty, an assistant professor in the department, said he is inspired by the accomplishments of his research group and “thrilled to see the efforts of my students recognized in this way.”

David W. Flaherty
David W. Flaherty

The Flaherty Research Group develops new principles needed to design catalytic materials and systems for the sustainable production of consumer products and fuels.

“This difficult work is only possible because of the many forms of support we receive from our department and from the campus. Interactions with exceptional colleagues and the use of outstanding facilities are a few of the ways in which Illinois cultivates excellent research. I am honored for our group to be acknowledged along with the many brilliant engineers at Illinois,” he said.

Flaherty, who joined the department in 2012, holds a BS from University of California, Berkeley and a PhD from the University of Texas at Austin.

Harley said it was a humbling to receive such an award.

Brendan A. Harley
Brendan A. Harley

“There are amazing faculty doing innovative, meaningful research across this campus. To be recognized in this manner is a tribute to the outstanding trainees in my group who everyday work to make science bigger, more rigorous, and more inclusive,” said Harley, associate professor and Robert W. Schaefer Faculty Scholar. “It is also a reflection of my colleagues, collaborators, as well as the facilities and support staff on this campus who make our work possible.”

The Harley Research Group explores “how we can design biomaterials that can be implanted into the body to facilitate regeneration. But we also are developing biomaterials to examine biological processes outside of the body such as disease development and treatment.”

“Our challenge is to develop materials that mimic the complex, heterogeneous environment within the tissues and organs of our body,” Harley said. “We are excited about the potential of our work, such as finding new ways to predict drug resistance and patient-to-patient variability in cancer as well as to implants to regenerate complex musculoskeletal injuries such as composite (hard and soft tissue) craniofacial defects experienced by warfighters after high-energy impacts.”

Harley joined the department in 2008. He holds an SB degree from Harvard University and an SM/ScD from MIT.

Congratulations to Dr. Takahiko Moteki who won the 2017 Outstanding Young Researcher Award from the Society of Chemical Engineers, Japan for his work on ethanol conversion in the Flaherty Research Group.

The citation was for “Ethanol upgrading via cascade C-C bond formation reactions.” The work was performed with the Energy Biosciences Institute with financial support from BP.

Moteki was a postdoctoral researcher in Dr. Flaherty’s group from October 2014 to October 2016. His research focused on developing strategies to form renewable chemicals and fuels from ethanol created by the fermentation of biomass. His work elucidated the reaction networks responsible for oligomerizing ethanol derived intermediates into larger species and demonstrated methods to control these networks to selectively produce either long chain alcohols or aromatic compounds.

Dr. Moteki is now an assistant professor in the Department of Chemical System Engineering at the University of Tokyo.

Congratulations Professor Moteki!


A new, multimillion dollar bioenergy research center at the University of Illinois that promises to be a catalyst for the development of sustainable, cost-effective biofuels and bioproducts will involve several faculty from Chemical and Biomolecular Engineering.

The Department of Energy announced earlier this summer it has awarded the University of Illinois $104 million for the Center for Advanced Bioenergy and Bioproducts Innovation (CABBI). The center is a collaboration between Illinois’ Institute for Sustainability, Energy, and Environment (iSEE) and the Carl R. Woese Institute for Genomic Biology (IGB), and will include 17 partner institutions.

“As the United States seeks energy independence, we need to look at the most efficient ways to grow, transform, and market biofuels,” said Evan H. DeLucia, the G. William Arends Professor of Plant Biology and Baum Family Director of iSEE. DeLucia will serve as CABBI Director. “This grant is a game-changer, and CABBI will be at the forefront as we press toward a new bio-based economy. Our center’s holistic approach will generate new products directly from biomass, reducing our nation’s dependence on fossil fuels and making us more secure.”

CABBI is one of four Department of Energy Bioenergy Research Centers, joining the Great Lakes Bioenergy Research Center led by the University of Wisconsin, the Center for Bioenergy Innovation led by the DOE’s Oak Ridge National Laboratory, and the Joint Bioenergy Institute led by the DOE’s Lawrence Berkeley National Lab.

At Illinois, researchers will develop fuels and products by integrating three interconnected priority areas: Growing the Right Crops (feedstock development), Turning Plants into Fuel (conversion), and Determining the Environmental and Economic Bottom Line (sustainability). Crop Sciences professor Stephen Moose will lead the feedstock development theme, in which scientists will integrate recent advances in genomics, synthetic biology, and computational biology to increase the value of biomass crops. Madhu Khanna, ACES Distinguished Professor in Environmental Economics in the Department of Agricultural and Consumer Economics, will lead the sustainability theme in which researchers will provide an overarching framework for viewing outcomes from the feedstocks and conversion themes through an environmental and economic lens.

Dr. Huimin Zhao in his lab at the Carl R. Woese Institute for Genomic Biology

Dr. Huimin Zhao, the Steven L. Miller Chair in Chemical Engineering at Illinois, will lead the conversion area. His team of about 19 principal investigators, which include two other ChBE faculty at Illinois—Professor Chris Rao and Assistant Professor David Flaherty—will further develop a versatile, automated “biofoundry” for rapidly engineering microbial strains that can efficiently produce diverse, high-value molecules such as biodiesel, organic acids, jet fuels, lubricants, and alcohols. Using the design-build-test-learn framework, research in the conversion theme will overcome the challenges associated with driving biological systems to produce non-natural compounds.

“It’s a unique vision. We want to use the plants as the factories to produce lipid-based chemicals and then we’ll couple that with the microbial conversion platform to make more high-value added products. Furthermore, we will use the lignocellulose from those plants as the feedstocks to make a wide variety of chemicals,” Zhao said.

This approach is different from the other three existing bioenergy centers funded by the Department of Energy, he said. The other centers focus their work on developing technologies to deconstruct the lignocellulose to generate fermentable sugars like glucose and xylose and using those sugars to make a variety of fuels and chemicals.

He and his team of researchers also want to understand what constrains the production of those biofuels or chemicals in the microorganisms. And they want to produce more chemicals and biofuels as well. That’s why Zhao has brought in experts in catalysis like Dr. David Flaherty who will develop chemical catalysts to upgrade the fuels and chemicals produced by the microorganisms.

Dr. David Flaherty

Flaherty’s group will be collaborating with others in CABBI to develop catalysts to convert advantaged molecules produced from microorganisms, such as butanol and unsaturated fatty acids, into clean burning fuels. They’ll also be coproducing high value chemicals to help increase the economic viability of the overall process.

“The networks of catalytic reactions in these systems are incredibly complex, and to be successful, we will need to develop maps of the reaction pathways that exist and use that information to identify opportunities to control the selectivity to specific desired products,” Flaherty said.

Dr. Christopher Rao

Dr. Chris Rao will focus on the engineering of oleaginous yeast to produce biofuels and chemicals and to understand what constrains the production of those products in the yeast.

“If you think from the organisms’ point of view, they don’t want to produce the product we want at large amounts because it will not benefit their survival and growth. … So we have to hijack the native metabolism to make the organisms themselves produce the product we want,” Zhao said.

The goal of metabolic engineering is to essentially engineer microorganisms to produce useful chemicals, but if they produce at low levels, that would not be economical, Zhao said. How does one make the organism produce a lot of product in a very short period of time? That’s another challenge researchers will address.

“In the traditional chemical industry, what a chemist or chemical engineer often does is to develop chemical catalysts and use them to convert non-renewable petroleum oils into fuels and chemicals. Now we want to develop biological catalysts such as microorganisms and enzymes and use them to convert renewable plant biomass into fuels and chemicals, which represents a paradigm shift in the chemical industry,” Zhao said.

Zhao, Rao and Flaherty have collaborated before. All three were involved with the Energy Biosciences Institute, which was established in 2007 as a partnership between Illinois and the University of California at Berkeley and Lawrence Berkeley National Lab, with initial funding from BP. Because of their work with EBI, Illinois had a strong track record of collaboration and accomplishments in bioenergy research and an infrastructure in place, Zhao said.

At the Carl R. Woese Institute for Genomic Biology, Zhao leads the Biosystems Design theme and he has been involved in development of the Illinois Biological Foundry for Advanced Biomanufacturing, or iBioFAB. Housed at IGB, iBioFAB is a computational and physical infrastructure that supports rapid design, fabrication, validation/quality control, and analysis of genetic constructs and organisms.

IGB will oversee and integrate CABBI’s core science team under one roof.

“The IGB, now with over a decade of experience in successfully addressing grand challenges by transdisciplinary integration of the life sciences, physical sciences, and engineering, will provide an outstanding environment for the talented CABBI team,” said director Gene Robinson.

The Institute for Sustainability, Energy, and Environment will coordinate and integrate field work off campus and at the Illinois Energy Farm, a 320-acre site that enables researchers to trial promising biofuel feedstocks at scale, and it will utilize the nearly complete, $32 million Integrated Bioprocessing Research Laboratory.

“We are very excited about this project because this will further build on our strengths in this area. This is definitely the future. I’m pleased the Department of Energy is committed to this direction,” Zhao said.

The center is expected to receive $4 million in fiscal year 2018, then $25 million a year in 2019-22.

Partner institutions include Brookhaven (N.Y.) National Laboratory; the Lawrence Berkeley National Laboratory’s Joint Genome Institute in Berkeley, Calif.; the U.S. Department of Agriculture’s (USDA) Agricultural Research Service (ARS) in Houma, La., the USDA ARS in Peoria, Ill.; Iowa State University; Princeton University; Mississippi State University; the University of California-Berkeley; West Virginia University; Boston University; the University of Wisconsin-Madison; Colorado State University; the University of Idaho; the University of Florida; the University of Nebraska; the Institute for Systems Biology in Seattle; and the HudsonAlpha Institute for Biotechnology in Huntsville, Ala.

The Department of Energy’s Bioenergy Research Program was established in 2007 and has led to 2,630 peer-reviewed publications, 607 invention disclosures, 378 patent applications, 191 licenses or options, 92 patents, and 14 start-up companies.

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