Christopher Burcham

For More Information

• LinkedIn

Chapters in Books

• Derdour, Lotfi, Stradiotto, David, and Burcham, Christopher L. (2026). “Chapter 1. Introduction: Drug Substance Crystallization Objectives.” Chapter 1 in Crystallization of Active Pharmaceutical Ingredients: Practical Approaches, Advances, and Trends, Lotfi Derdour (ed). John Wiley and Sons.
• Burcham, Christopher L., Green, Daniel A., and Kulkarni, Samir (2026). “Chapter 2. Phenomena Involved in Particle Formation.” Chapter 2 in Crystallization of Active Pharmaceutical Ingredients: Practical Approaches, Advances, and Trends, Lotfi Derdour (ed). John Wiley and Sons.
• Kelkar, Manish, Derdour, Lotfi, Nere, Nandkishor K., and Burcham, Christopher L. (2026). “Chapter 13. Evolution of Crystallization Objectives and Deliverables with Phases of Drug Development.” Chapter 13 in Crystallization of Active Pharmaceutical Ingredients: Practical Approaches, Advances, and Trends, Lotfi Derdour (ed). John Wiley and Sons.
• Seibert, Kevin D., Burcham, Christopher L., Jarmer, Daniel, Luciani, Carla V., Collins, Paul C. and Fisher, Elizabeth S. (2026). “Chapter 38: Milling Operations in the Pharmaceutical Industry.” Chapter 38 in Chemical Engineering in the Pharmaceutical Industry, Mary T. am Ende, David J. am Ende (ed). John Wiley and Sons.
• Mitchell, N. A., Bermingham, S. K., Burcham, C. L., Polster, C., Tahir, F. and Mack, J. (2020). “Using Quality by Design Principals as a Guide for Designing a Process Control Strategy: Digital Design and Operation of Continuous Crystallization Processes via Mechanistic Modelling Tools.” Chapter 16 in The Handbook of Continuous Crystallization. Yazdanpandah, N., and Nagy, Z. (eds), The Royal Society of Chemistry,
• Hilden, J., Burcham, C.L., Stamatis, S.D., Miesle, J., and Coutant, C.A. (2018). “Guidance on Drug Substance Particle Size Controls to Achieve Adequate Uniformity of Dosage Units.” Chapter 7 in Particles and Nanoparticles in Pharmaceutical Products: Design, Manufacturing, Behavior and Performance, Volume 29 of AAPS Advances in the Pharmaceutical Sciences Series, eds. Merkus, H.G., Meesters, G.M.H., and Oostra, W.
• Burcham, C. L., LaPack, M., Martinelli, J. R., and McCracken, N. (2017). “Using Quality by Design Principals as a Guide for Designing a Process Control Strategy” Chapter 7 in Comprehensive Quality by Design for Pharmaceutical Product Design and Manufacture. Reklaitis, G. V., Seymour, C., and Garcia-Munoz, S. (eds), Wiley
• Burcham, C. L., Collins, P. C., Jarmer, D. J., and Seibert, K. D. (2008). “Chapter 8: Reduction of Particle Size of Drug Substance for Low-Dose Drug Products.” Book chapter in Formulation and Analytical Development for Low-Dose Oral Drug Products. Zheng, J. (ed.), John-Wiley and Sons, Inc., 205-222

Selected Articles in Journals

• Lempert, W. R., Harris, S. R., Magee, K., Burcham, C. L., Saville, D. A., Miles, R. B., Gee, K. R., and Haughland, R. P., (1994). “Flow Tagging in Water Using Nonintrusive Tracking of Molecular Motion (PHANTOMM).” Proceedings of the 7th International Symposium on Applications of Laser Techniques to Fluid Mechanics, Lisbon, Portugal.
• Pletser, V., Burcham, C. L., and Cronise, R., (1995). “A BDPU Preparatory Experiment for Spacelab LMS During Parabolic Flights with the NASA-LeRC DC-9 Aircraft.” Microgravity News from ESA, 8, 3, pp.4-10.
• Harris, S. R., Burcham, C. L., Gee, K., Haughland, R. P., Hersch, L., Lempert, W. R., Miles, R. B., and Saville, D. A. (1996). “Quantitative Measurements of Internal Circulation in Droplets using Flow Tagging Velocimetry.” American Institute of Aeronautics and Astronautics Journal, 34, 3, pp. 449-454, doi.org/10.2514/3.13088.
• Burcham, C. L., Sankaran, S., and Saville, D. A., (1998). “Electrohydrodynamic Stability of a Liquid Bridge – The Alex Experiment.” Proceedings of the 4th Microgravity and Fluid Physics Conference, Aug.12-14, 1998, Cleveland, Ohio.
• d’Hooghe, E. L., Burcham, C. L., and Edwards, C. M., (1999). “Thermoforming and Recycling of Fulcrum* Thermoplastic Composites.” 1999 Proceedings of the 27th Annual Conference of SPI Structural Plastics Division.
• Burcham, C. L. and Saville, D. A., (2000). “The Electrohydrodynamic Stability of a Liquid Bridge: Microgravity Experiments on a Bridge Suspended in a Dielectric Gas.” Journal of Fluid Mechanics, 405, pp. 37-56, doi.org/10.1017/S0022112099007193.
• Burcham, C. L. and Saville, D. A., (2002). “Electrohydrodynamic Stability: Taylor-Melcher Theory for a Liquid Bridge Suspended in a Dielectric Gas.” Journal of Fluid Mechanics, 452, pp. 163-187, doi.org/10.1017/S0022112001006784.
• Iacocca, R. G., Burcham, C. L. and Hilden L. R. (2010). “Particle Engineering: A Strategy for Establishing Drug Substance Physical Property Specifications during Small Molecule Development.” Journal of Pharmaceutical Sciences, 99(1), pp. 51-75, doi.org/10.1002/jps.21801.
• Vetter, T., Burcham, C. L., and Doherty, M. F. (2014). “Regions of Attainable Particle Sizes in Continuous and Batch Crystallization Processes.” Chem. Eng. Sci., 106, 167-180, doi.org/10.1016/j.ces.2013.11.008.
• Polster, C. P, Cole, K. P., Burcham, C. L., Campbell, B. M., Frederick, A. M., Hansen, M. H., Harding, M., Heller, M. R., Miller, M. T., Phillips, J. L., Pollock, P. M., and Zaborenko, N. (2014). “Pilot-scale Continuous Production of LY2886721: Amide Formation and Reactive Crystallization,” OPRD, 18, 1295-1309, doi.org/10.1021/op500204z.
• Vetter, T., Burcham, C. L., and Doherty, M. F., (2014). “Attainable Regions in Crystallization Processes: Their Construction and the Influence of Parameter Uncertainty.” Computer Aided Chemical Engineering, 34, 465-470, doi.edu/10.1016/B978-0-444-63433-7.50062-6.
• Vetter, T., Burcham, C. L., and Doherty, M. F., (2015). “Separation of Conglomerate Forming Enantiomers Using a Novel Continuous Preferential Crystallization Process.” AIChE Journal, 61, 2810-2823, doi.org/10.1002/aic.14934.
• Vetter, T., Burcham, C. L., and Doherty, M. F., (2015). “Designing robust crystallization processes in the presence of parameter uncertainty using attainable regions.” Journal of Industrial Engineering Chemistry, 54, 42, 10350-10363, doi.org/10.1021/acs.iecr.5b00693.
• Peña, R., Olivia, J.A., Burcham, C. L., Jarmer, D. J. and Nagy, Z. K. (2017). “Process intensification through continuous spherical crystallization using an oscillatory flow baffled crystallizer (OFBC).” Crystal Growth & Design, 17 (9), 4776-4784, doi.org/10.1021/acs.cgd.7b00731.
• Peña, R., Burcham, C. L., Jarmer, D. J., Ramkrishna, D. and Nagy, Z. (2017). “Modeling and Optimization of Spherical Agglomeration in Suspension through a Coupled Population Balance Framework.” Chem. Eng. Sci., 167, pp 66-77, doi.org/10.1016/j.ces.2017.03.055.
• Cole, K. P., McClary-Groh, J., Johnson, M. D., Burcham, C. L., Campbell, B. M., Diseroad, W. D., Heller, M. R., Howell, J. R., Kallman, N. J., Koenig, T. M., May, S. A., Miller, R. D., Mitchell, D., Myers, D. P., Myers, S. S., Phillips, J. L., Polster, C. P., White, T. D., Cashman, J., Hurley, D., Moylan, D., Sheehan, P. , Spencer, R.D., Desmond, K., Desmond, P. and Gowran, O. (2017). “Kilogram-Scale Preparation of Prexasertib Monolactate Monohydrate Synthesis under Continuous-Flow cGMP Conditions.” Science, 356, pp. 1144-1150, doi.org/10.1126/science.aan0745.
• Burcham, C. L., Florence, A. J., and Johnson, M. D. (2018). “Continuous Manufacturing in Pharmaceutical Process Development and Manufacturing.” Annual Review of Chemical and Biomolecular Engineering, 9, 253 – 281, doi.org/10.1146/annurev-chembioeng-060817-084355.
• Acevedo, D., Jarmer, D. J., Burcham, C. L., Polster, C. P. and Nagy, Z. K. (2018). “A Continuous Multi-Stage Mixed-Suspension Mixed-Product-Removal Crystallization System with Fines Destruction.” Chem. Eng. Res. Des., 135, pp. 112-120, doi.org/10.1016/j.cherd.2018.05.029.
• Peña, R., Pal, K., Burcham, C. L., Jarmer, D. J., and Nagy, Z.K. (2019). “Further understanding of agglomeration mechanisms in spherical crystallization systems; benzoic acid case study.” Crystal Growth and Design, 19 (3), 1668-1679, doi.org/10.1021/acs.cgd.8b01519.
• Burcham, C.L. and Singh, M. R. (eds). (2019). “Modeling and Control of Crystallization.” Special Issue of Process, 7 (5), https://www.mdpi.com/journal/processes/special_issues/crystallization_modeling.
• Abdullahi, Hassan., Vetter, Thomas., Burcham, Christopher L., (2020). “A Mechanistic Model to Predict Droplet Drying History and Particle Shell Formation in Multicomponent Systems” Chemical Engineering Science, 224, 115713, doi.org/10.1016/j.ces.2020.115713
• Abdullahi, Hassan., Vetter, Thomas., Burcham, Christopher L., (2021). “Single Droplets to Particles – Size, Shape, Shell Thickness and Porosity Analysis using X-ray Computed Tomography” Chemical Engineering Science, 245, 116879, doi.org/10.1016/j.ces.2021.116879.
• Pal, K., Szilagyi, B., Burcham, C. L., Jarmer, D. J., and Nagy, Z.K. (2021). “Iterative Model Based Experimental Design for Spherical Agglomeration Process.” AIChE Journal, 67, e17178, doi.org/10.1002/aic.17178.
• Szilagyi, Botond; Wu, Wei-Lee; Eren, Ayse; Mackey, Jaron; Kshirsagar, Shivani; Szilagyi, Emoke; Ostergaard, Iben; Qu, Haiyanm; Sinha, Kushal; Mlinar, Laurie; Pohlman, Daniel; Chen, Jie; Nere, Nandkishor; Boukerche, Moussa; Korde, Akshay; Ellis, Ryan; Lovette, Michael; Black, Simon; Jawor-Baczynska, Anna; Li, Huayu; Yang, Bing-Shiou; Irdam, Erwin; Patience, Daniel; McKeown, Rahn; Ketchum, Megan; Green, Daniel A.; Polster, Christopher; Burcham, Christopher; Jarmer, Daniel; Merritt, Jeremy Miles; Cote, Aaron; Sirota, Eric; Codan, Lorenzo; Schoell, Jochen; Liu, Yiqing Claire; Girard, Kevin P.; Kulkarni, Samir A.; Yang, Yihui; Quon, Justin L.; and Nagy, Zoltan K. (2021). “Cross-pharma collaboration for the development of a simulation tool for the model based digital design of pharmaceutical crystallization processes (CrySiV).” Crystal Growth and Design, 21, 11, pp 6448-6464, doi.org/10.1021/acs.cgd.1c00904.
• Wu, Wei-Lee, Oliva, Joe, Kshirsagar, Shivani, Burcham, Christopher L., and Nagy, Zoltan K. (2021). “Continuous In Situ Seed Generation through the Integration of a Mixed Suspension Mixed Product Removal and an Oscillatory Baffled Crystallizer for the Control of Crystal Size Distribution and Polymorphic Form.” Crystal Growth and Design, 21, 12, 6684-6696, doi.org/10.1021/acs.cgd.1c00301.
• Zhang, Shawn, Stroud, Paul A., Zhu, Aiden, Johnson, Michael J., Lomeo, Joshua, Burcham, Christopher L., Hinds, Jeremy, and Blakely, Kyle Allen-Francis, (2021). “Characterizing the Impact of Spray Dried Particle Morphology on Tablet Dissolution Using Quantitative X-Ray Microscopy.” European Journal of Pharmaceutical Sciences, 165, doi.org/10.1016/j.ejps.2021.105921.
• Johnson, Martin D., Burcham, Christopher L., May, Scott A., Calvin, Joel R., McClary-Groh, Jenifer, Myers, Steven S., Webster, Luke P., Roberts, Jeffrey C., Reddy, V. Ramana, Luciani, Carla V., Corrigan, Aoife P., Spencer, Richard D., Moylan, Robert, Boyse, Raymond, Murphy, John D., Brody, Niamh, and Stout, James R. (2021). “API Continuous Cooling and Antisolvent Crystallization for Kinetic Impurity Rejection in cGMP Manufacturing.” Organic Process Research & Development, 25, 6, pp. 1284-1351, doi.org/10.1021/acs.oprd.0c00345.
• Jonuzaj, S., Burcham, C.L., Galindo, A., Jackson, G., Adjiman, C.S., (2022). “Optimizing the selection of drug-polymer-solvent formulations for spray-dried solid dispersions in pharmaceutical manufacturing.” Computer Aided Chemical Engineering, 49, 2185, doi.org/10.1016/B978-0-323-85159-6.50364-X.
• Jonuzaj, S., Burcham, C.L., Galindo, A., Jackson, G., and Adjiman, C. (2022). “Optimizing the selection of drug-polymer-solvent formulations for spray-dried solid dispersions in pharmaceutical manufacturing.” The 14th International Symposium on Process Systems Engineering, PSE2021+, June 19-23, 2022, Kyoto, Japan.
• Kocevska, Stefani, Burcham, Christopher, Nordstrom, Fredrik and Maggioni, Giovanni M. (2024). “A Changing Paradigm in Industrial Pharmaceutical Crystallization.” Nature Chemical Engineering, 1, 327-329 (Invited), doi.org/10.1038/s44286-024-00068-8.
• Burcham, Christopher L., Doherty, Michael F., Peters, Baron G., Price, Sarah L., Salvalaglio, Matteo, Reutzel-Edens, Susan M., Price, Louise S., Addula, Ravi Kumar Reddy, Francia, Nicholas, Khanna, Vikram, and Zhao, Yongsheng (2024). “Pharmaceutical Digital Design: From Chemical Structure through Crystal Polymorph to Conceptual Crystallization Process.” Crystal Growth and Design, 24, 13, 5417–5438, doi.org/10.1021/acs.cgd.3c01390.
• Svoboda, V., Burcham, C. L., Groh, J., Johnson, M. D., Merritt, J. M., Myers, S., and Stout, J., (2024). “In-situ Wet Milling for Particle Size Control in Continuous Crystallization: Expanding the Attainable Region.” Chemical Engineering Science, 300 120542, doi.org/10.1016/j.ces.2024.120542.
• Mustoe, C. L., Turner, A.J., Urwin, S.J., Houson, I., Feilden, H., Markl, D., Al Qaraghuli, M.M., Chong, M.W.S., Robertson, M., Nordon, A., Johnston, B.F., Brown, C.J., Robertson, J., Adjiman, C., Benyahia, B., Batchelor, H., Bresciani, M., Burcham, C.L., Cardona, J., Cottini, C., Dunn, A.S., Fradet, D., Halbert, G.H., Henson, M., Hidber, P., Langston, M., Lee, Y.S., Li, W., Mantanus, J., McGinty, J., Mehta, B;., Naz, T., Ottoboni, S., Prasad, E., Quist, P.O., Reynolds, G.K., Rielly, C., Rowland, M., Schlindwein, W., Schroeder, S.L.M., Sefcik, J., Settanni, E., Siddique, H., Smith, K., Smith, R., Srai, J.S., Thorat, A.A., Vassileiou, A., and Florence, A.J. (2025). “Quality by Digital Design to Accelerate Sustainable Medicines Development.” International Journal of Pharmaceutics, 681, 125625, doi.org/10.1016/j.ijpharm.2025.125625.

Articles in Conference Proceedings

• Harris, S. R., Lempert, W. R., Burcham, C. L., Saville, D. A. Miles, R. B., Hersch, L., Gee, K., and Haughland, R. (1995). “Quantitative Flow Visualization of Internal Circulation in Droplets by PHANTOMM (PHoto-Activated Nonintrusive Tracking Of Molecular Motion) Flow Tagging.” Proceedings of the American Institute of Aeronautics and Astronautics 33rd Aerospace Science Meeting and Exhibit, (AIAA-95-0168) Reno, NV.
• McAllister, K. A., Storms, S. M., Burcham, C. L., and DeFelippis, M. R. (2004). “Evaluation of a Closed System Device for Aseptic Sample Collection.” Abstracts, 36th Central Regional Meeting of the American Chemical Society, Indianapolis, IN, June 2-4, 2004.
• Burcham, C. L., Mersinger, J. L., Cronin, J. S., and Schafer, J.P. (2004). “Evaluation of the Particulate Capture Efficiency of the NovAseptic NovaSeptum Sterile Sampling System.” Abstracts, 36th Central Regional Meeting of the American Chemical Society, Indianapolis, IN, June 2-4, 2004.
• Martinelli, J. R., Varie, D. L., Burcham, C. L., LaPack, M. A., Parrish, A. R., Schneider, A. G., Yoder, J., and Robbins, C. N. (2009). “Design and Development of a Large Scale EDCI-Mediated Amide Bond Forming Reaction.” Abstracts of Papers, 238th ACS National Meeting, Washington, DC, August 16-20, 2009.
• Hoard, D. W., Burcham, C. L., Varie, D. L., and Towsley, R. W. (2011). “Establishing and preserving the amino-caprolactam stereochemistry in a key pharmaceutical intermediate.” Abstracts of Papers, 241st ACS National Meeting, Anaheim, CA, March 27-31, 2011.
• Vetter, T., Burcham, C. L., and Doherty, M. F., (2014). “Attainable Regions in Crystallization Processes: Their Construction and the Influence of Parameter Uncertainty.” Proceedings of the 8th International Conference on Foundations of Computer-Aided Process Design – FOCAPD, Eden, M., Sirola, J. D., and Towler, G. P. (eds.), Cle Elum, WA, July 13-14th, 2014.
• Burcham, C. L., and Mitchell, N. (2015) “Optimization of Continuous Crystallization Processes to Maintain Content Uniformity.” 2015 AIChE Annual Meeting Proceedings.
• Mitchell, N.A., Bermingham, S.K., Burcham, C. L., Polster, C.S., Girard, K. P. (2016). “Scale-up and Optimization of Filtration Processes: Pressure Filter to Centrifuge.” FILTECH 2016 Conference Proceedings.
• Mitchell, N.A., Burcham, C.L., Calado, F., and Myers, S. (2019). “Achieving particle size and impurity control for a continuous crystallization and wet milling process using a digital design approach.” Conference Proceedings AIChE Annual Meeting.
• Burcham, C. L., Polster, C., Girard, K. and Mitchell, N. A. (2022) “Scale-up and Optimization of Filtration Processes: Pressure Filter to Centrifuge.” Proceedings of the 13th World Filtration Congress, San Diego, CA.

Invited Lectures

• Burcham, C. L. (2014). “Particle Engineering in Pharmaceutical Product Development.” Invited Speaker, Purdue University, West Lafayette, IN, May 8th, 2014.
• Burcham, C. L. (2014). “Continuous Crystallization.” Invited Speaker, 1st Continuous Process Symposium, SK Life Science, Teaneck, NJ, May 14-15, 2014.
• Vetter, T., Burcham, C. L., and Doherty, M. F., (2014). “Attainable Regions in Crystallization Processes: Their Construction and the Influence of Parameter Uncertainty.” 8th International Conference on Foundations of Computer-Aided Process Design – FOCAPD, Cle Elum, WA, July 13-14th, 2014.
• Vetter, T., Burcham, C. L., and Doherty, M. F. (2014) “Which is More Important for Achieving the Desired PSD: Nucleation Law or Growth Law?” Process Systems Engineering Consortium Annual Meeting, Amherst, MA, July 25th, 2014.
• Vetter, T., Burcham, C. L., and Doherty, M. F. (2014) “Flexible continuous preferential crystallization processes using wet mills for in-situ generation.” 19th International Symposium on Industrial Crystallization (ISIC19), Toulouse, France, September 17-19, 2014.
• Burcham, C. L., Polster, C. S., and Bermingham, S. K. (2014). “Utilization of Batch Experiments to Develop a Continuous Cooled Antisolvent Crystallization Process.” 19th International Symposium on Industrial Crystallization (ISIC19), Toulouse, France, September 17-19, 2014.
• Burcham, C. L. (2014) “Continuous Crystallization in Pharmaceutical Manufacturing” Invited Speaker, 19th International Symposium on Industrial Crystallization (ISIC19), Toulouse, France, September 17-19, 2014.
• Vetter, T., Burcham, C. L., and Doherty, M. F. (2014) “Obtaining pure enantiomers and co-crystals using continuous preferential crystallization: a process development investigation using population balance models.” American Institute of Chemical Engineers Annual Meeting, Atlanta, GA, November 16-21, 2014.
• Burcham, C. L., and Mitchell, N. (2015) “Optimization of Continuous Crystallization Processes to Maintain Content Uniformity.” American Institute of Chemical Engineers Annual Meeting, Salt Lake City, UT, November 8-13, 2015.
• Burcham, C. L. (2015). “Particle Engineering in Pharmaceutical Product Development.” Invited Speaker, Purdue University, West Lafayette, IN, March 31st and April 2nd, 2015.
• Acevedo, D., Burcham, C. L., Jarmer, D. J. and Nagy, Z. (2016) “Optimization of Batch and Continuous Cooling Crystallization of High Aspect Ratio Crystals under Nucleation, Growth, Dissolution and Breakage for Shape Control.” 2016 American Institute of Chemical Engineers Midwest Regional Conference, Chicago, IL, March 3-4, 2016.
• Peña, R., Burcham, C. L., Jarmer, D. J., Ramkrishna, D. and Nagy, Z. (2016) “Modeling and optimization of spherical crystallization through a coupled population balance framework.” 2016 American Institute of Chemical Engineers Midwest Regional Conference, Chicago, IL, March 3-4, 2016.
• Burcham, C. L. (2016) “Continuous Processing in the Pharmaceutical Industry: Challenges and Opportunities.” 2016 American Institute of Chemical Engineers Midwest Regional Conference, Chicago, IL, March 3-4, 2016.
• Burcham, C. L. (2016) “Continuous Processing in Pharmaceutical Product Development.” Invited Lecturer, University of Strathclyde and CMAC, Glasgow, United Kingdom, May 6, 2016.
• Burcham, C. L. (2016). “Particle Engineering in Pharmaceutical Product Development.” Invited Speaker, Purdue University, West Lafayette, IN, April 5th and 7th, 2016.
• Burcham, C. L., and Mitchell, N. (2016) “Optimization of Continuous Crystallization Processes to Maintain Content Uniformity.” Invited Speaker, APM2016; The Advanced Process Modeling Forum, London, UK, April 20-21. 2016.
• Burcham, C. L. (2016) “Particle Engineering in Pharmaceutical Product Development.” Invited Lecturer, University of Manchester, Manchester, United Kingdom, September 23, 2016.
• Burcham, C. L., Polster, C., Girard, K. and Mitchell, N. A. (2016) “Scale-up and optimization of filtration processes: Pressure filter to Centrifuge.” FILTECH 2016 Conference, Cologne, Oct. 11-13, 2016.
• Peña, R., Nagy, Z., Burcham, C. L., and Jarmer, D. J. (2016). “Process Intensification Through Continuous Spherical Crystallization using an Oscillatory Baffled Crystallizer.” American Institute of Chemical Engineers Annual Meeting, San Francisco, CA, November 13-18, 2016.
• Peña, R., Nagy, Z., Ramkrishna, D., Burcham, C. L., and Jarmer, D. J. (2016). “Modeling and Optimization of Agglomeration in Suspension through a Coupled Population Balance Framework.” American Institute of Chemical Engineers Annual Meeting, San Francisco, CA, November 13-18, 2016.
• Acevedo, D., Burcham, C. L., Jarmer, D. J. and Nagy, Z. (2016). “Optimization of Batch and Continuous Cooling Crystallization of High Aspect Ratio Crystals under Nucleation, Growth, Dissolution and Breakage for Shape Control.” American Institute of Chemical Engineers Annual Meeting, San Francisco, CA, November 13-18, 2016.
• Blakely, K. A. F., and Burcham, C. L. (2016). “Solid State Form Understanding Applied to the Design of a Spray Dried Dispersion Process: A Quality by Design Approach to Optimization of Feed Solution Loading.” American Institute of Chemical Engineers Annual Meeting, San Francisco, CA, November 13-18, 2016.
• Burcham, C. L. (2016) “Integration of Downstream Unit Operations in Crystallization Process Design.” Invited Speaker, PSE Webinar Series, London, UK, December 14. 2016.
• Abdullahi H., Vetter T., and Burcham C., (2017). “Towards the morphology of particles obtained from spray drying.” British Association of Crystal Growth Research Conference, Manchester, UK, June 27-30, 2017.
• Pal, K., Peña, R., Nagy, Z. K., Burcham, C. L., and Jarmer, D. J. (2017) “Mechanistic Study on Co-agglomeration of Active Pharmaceutical Ingredients and Excipients.” 2017 American Institute of Chemical Engineers Midwest Regional Conference, Chicago, IL, February 28 – March 1, 2017.
• Pal, K., Olivia, J.A., Peña, R., Nagy, Z. K., Burcham, C. L., and Jarmer, D. J. (2017) “Optimization of Binder Addition for Spherical Agglomeration in Oscillatory Baffled Crystallizers.” 2017 American Institute of Chemical Engineers Midwest Regional Conference, Chicago, IL, February 28 – March 1, 2017.
• Burcham, C. L. (2017). “Particle Engineering in Pharmaceutical Product Development.” Invited Speaker, Purdue University, West Lafayette, IN, April 11th and 13th, 2017.
• Burcham, C. L., Myers, S. S., and Mitchell, N. A. (2017) “Attainable Regions for Critical Quality Attributes in Drug Manufacture and End Performance.” 20th International Symposium on Industrial Crystallization (ISIC20), Dublin, Ireland, September 3-6, 2017.
• Polster, C., McClary-Groh, J., Cole, K. P., and Burcham, C. L. (2017) “Continuous Crystallization and Transient Isolation of a GMP Intermediate.” 20th International Symposium on Industrial Crystallization (ISIC20), Dublin, Ireland, September 3-6, 2017.
• Polster, C., Mitchell, N. A., and Burcham, C. L. (2017) “Impact of an Impurity on the Morphology and Growth Kinetics of an Investigational API.” 20th International Symposium on Industrial Crystallization (ISIC20), Dublin, Ireland, September 3-6, 2017.
• Abdullahi, Hassan, Vetter, Thomas, and Burcham Christopher L. (2017). “Towards Modelling the Morphology of Particles Obtained from Spray Drying.” Institute of Chemical Engineers (IChemE's) Biochemical Engineering Special Interest Group (BESIG) Young Researchers Meeting, Univ. College London, London, UK, September 13, 2017.
• Mitchell, N. A., Polster, C., Burcham, C. L., Girard, K. and Bermingham, S. P. (2017) “Scale-up and Optimization of Filtration processes: Small Scale Pressure Filtration to Centrifugal Filtration.” American Institute of Chemical Engineers Annual Meeting, Minneapolis, MN, October 29-November 3, 2017.
• Pal, K., Burcham, C. L., Jarmer, D. J., Nagy, Z.K. (2017). “Use of process analytical technology to gain mechanistic insights into spherical agglomeration of active pharmaceutical ingredients.” American Institute of Chemical Engineers Annual Meeting, Minneapolis, MN, October 29-November 3, 2017.
• Rogers, R. E., Cash, K. J., Burcham, C. L., Mountziaris, T. J. and Wu, J. S. (2017) “Panel Discussion: Funding Your Research.” American Institute of Chemical Engineers Annual Meeting, Minneapolis, MN, October 29-November 3, 2017.
• Abdullahi, Hassan, Vetter, Thomas, and Burcham Christopher L. (2017). “Towards Modelling the Morphology of Particles Obtained from Spray Dried Droplets.” 6th International Conference on Population Balance Modelling (PBM2018) , Ghent, Belgium, May 7, 2018.
• Burcham, C. L., Lovette, M. A., Polster, (2017). “Using gCrystal in the Design of Continuous Crystallizations.” Systems Based Pharma Consortium Annual Meeting, Philadelphia, PA, Oct, 2017.
• Burcham, C. L., (2017). “Commencement Address”, Department of Chemical Engineering Winter Convocation, Keynote Speaker, University of Illinois, December 22, 2017
• Burcham, C. L. (2018). “Crystallization Process Development in Pharmaceutical Product Development.” Invited Speaker, Purdue University, West Lafayette, IN, April 17th and 19th, 2018.
• Changi, S. M., Buser, J. Y., Embry, M. C., Jarmer, D., Burcham, C. L., Vaid, R. K., McFarland, A. D., Pletcher, T., Luciani, C., Kearney, K., Mullane N., and Hurley, D. D. (2018). “A Case Study and Design Considerations for the Robust Removal of Dissolved Hydrogen Chloride. ” American Institute of Chemical Engineers Annual Meeting, Pittsburgh, PA, October 28-November 2, 2018.
• Burcham, C. L. (2018). “Learning From Failure: When impurities interrupt particle size control.” Invited Speaker, Association of Crystallization Technology, 22nd Larson Conference, Cambridge, MA, September 30 - October 3, 2018.
• Burcham, C. L., Polster, C.S., Groh, J.M., and Cole, K.P. (2018). “Continuous Crystallization and Transient Isolation of a cGMP Intermediate.” Invited Speaker, Association of Crystallization Technology, 22nd Larson Conference, Cambridge, MA, September 30 - October 3, 2018.
• Wu, Wei-Lee, Su, Qingling, Burcham, Christopher L., and Nagy, Zoltan K. (2019). “Continuous in-situ Seed Generation and Polymorphic Control using a Novel MSMPR-COBC Combination Approach.” Purdue Chemical Engineering Graduate Research Symposium Purdue University, Lafayette, IN, August 15, 2019.
• Abdullahi H., Vetter T., and Burcham C., (2019). “Analysis of the microstructure of particles obtained by evaporating acoustically levitated single droplets using X-ray computed tomography.” Formula X Conference, Manchester, UK.
• Abdullahi Hassan., Vetter Thomas., Burcham Christopher L., (2019). “Utilizing modelling approaches for the scale up of spray dryers.” Royal Society of Chemistry – Formula X Conference, Manchester, UK, June 24 – 27, 2019.
• Burcham, Christopher L. (2019). “Keynote Speaker: Transition from Graduate School to Industry.” Purdue Chemical Engineering Graduate Research Symposium Purdue University, Lafayette, IN, August 15, 2019.
• Burcham, Christopher L. (2019). “Development of a Pharmaceutical Continuous Crystallization Processes.” Particulate Processes: From Theory to Application organized by the International Max Planck Research School (IMPRS), Magdeburg, Germany, August 26 – 30, 2019.
• Burcham, Christopher L. (2019). “Establishing API Physical Property Requirements and Development of the Crystallization Processes to Achieve Them.” Particulate Processes: From Theory to Application organized by the International Max Planck Research School (IMPRS), Magdeburg, Germany, August 26 – 30, 2019.
• Abdullahi, Hassan, Burcham Christopher L., and Vetter, Thomas (2019). “Analysis of the microstructure of particles obtained by evaporating acoustically levitated single droplets using X-ray computed tomography.” 12th European Congress of Chemical Engineering, 5th European Congress of Applied Biotechnology, Florence, Italy, September 15-19, 2019.
• Burcham, Christopher L. (2019). “Translating Academic Research into Industrial Benefits: CMAC PhD Placements.” CMAC UK Showcase, Glasgow, Scotland, October 23 – 35, 2019.
• Abdullahi, Hassan, Burcham Christopher L., and Vetter, Thomas (2019). “Towards Modelling the Morphology of Particles Obtained from Spray Dried Droplets.” American Institute of Chemical Engineers Annual Meeting, Orlando, FL, November 10-15, 2019.
• Abdullahi, Hassan, Burcham Christopher L., and Vetter, Thomas (2019). “Analysis of the microstructure of particles obtained by evaporating acoustically levitated single droplets using X-ray computed tomography.” American Institute of Chemical Engineers Annual Meeting, Orlando, FL, November 10-15, 2019.
• Mitchell, Niall, Burcham Christopher L., Calado, Filipe, and Myers, Steven S. (2019). “Achieving particle size and impurity control for a continuous crystallization and wet milling process using a digital design approach.” American Institute of Chemical Engineers Annual Meeting, Orlando, FL, November 10-15, 2019.
• Burcham, C. L. (2020). “After Graduate School: The transition to industry… a twenty-two year journey” CMAC PhD Training Conference, February 28th, 2020.
• Burcham, Christopher L. (2020). “On application to population balances in continuous crystallization.” 12th Annual American Institute of Chemical Engineers Midwest Regional Conference, Chicago, IL, March 11 – March 12, 2020.
• Burcham, C. L. (2020). “Crystallization Process Development in Pharmaceutical Product Development.” Invited Speaker, Purdue University, West Lafayette, IN, April 16th, 23rd, and 30th, 2020.
• Burcham, C. L. (2020). “Multi-Dimensional Population Balance Models.” CMAC Technical Community Discussion, May 21st, 2020.
• Burcham, C. L. (2020). “Continuous Processing in Pharmaceutical Product Development: Application of Continuous Crystallization” Invited Speaker – Virtual Seminar Series, Georgia Institute of Technology, Atlanta, GA, August 26th, 2020.
• Burcham, C. L., Calado, F., Mitchell, N., Stout, J. R., Johnson, M.D., Groh, J.M., Myers, S., and Svoboda, V. (2020). “Development of a Continuous Crystallization with Periodic Wet Milling for Particle Size Control.” Invited Keynote Speaker, Working Party on Crystallization, European Federation of Chemical Engineers, Webinar Series, September 9th – 11th, 2020.
• Barrasso, Dana, Bermingham, Sean K., Fischer, Kerri and Burcham Christopher L. (2020). “Web deployment of mechanistic models for pharmaceutical applications: Case studies in spray drying and distillation.” American Institute of Chemical Engineers Annual Meeting, San Francisco, CA, November 15-20, 2020.
• Mitchell, Niall, Burcham Christopher L., Calado, Filipe, Pereira, S. and Myers, Steven S. (2020). “Digital design via mechanistic modelling of a continuous crystallization process with periodic wet milling.” American Institute of Chemical Engineers Annual Meeting, San Francisco, CA, November 15-20, 2020.
• Wu, Wei-Lee, Oliva, Joseph A., Khirsagar, Shivani, Burcham Christopher L., and Nagy, Zoltan K. (2020). “Novel integration of continuous crystallization platforms for control of crystal size distribution and polymorphic form.” American Institute of Chemical Engineers Annual Meeting, San Francisco, CA, November 15-20, 2020.
• Burcham, C. L. (2020). “Crystallization Process Development in Pharmaceutical Product Development.” Invited Speaker, Purdue University, West Lafayette, IN, November 3rd, 2020.
• Burcham, C. L., Svoboda, V., Myers, S., Groh, J.M., Johnson, M.D., Merritt, J.M., Reddy, V.R., Stout, J. R., Mitchell, N., Calado, F., and Pereira, S. (2021). “Inline Wet Milling For Particle Size Control in Continuous Crystallization.” CMAC Training programme, May 21st, 2021.
• Burcham, C. L., Linder, S., Gore, D. and Hashen, N. (2021). “Industry vs. Academia & The Importance of Diverse Thought and Inclusivity in Industry.” Invited Lecture, University of Illinois - Chemistry 592, , March 22nd, 2021.
• Johnson, Martin D., Burcham, Christopher L., May, Scott A., Calvin, Joel R., McClary-Groh, Jenifer, Myers, Steven S., Webster, Luke P., Roberts, Jeffrey C., Reddy, V. Ramana, Luciani, Carla V., Corrigan,, Aoife P., Spencer, Richard D., Moylan, Robert, Boyse, Raymond, Murphy, John D., Brody, Niamh, and Stout, James R. (2021). “API Continuous Cooling and Antisolvent Crystallization for Kinetic Impurity Rejection in cGMP Manufacturing.” Pharmaceutical Manufacturing and Packaging Congress, BGS online, June 28-29, 2021.
• Johnson, Martin D., Burcham, Christopher L., May, Scott A., Calvin, Joel R., McClary-Groh, Jenifer, Myers, Steven S., Webster, Luke P., Roberts, Jeffrey C., Reddy, V. Ramana, Luciani, Carla V., Corrigan,, Aoife P., Spencer, Richard D., Moylan, Robert, Boyse, Raymond, Murphy, John D., Brody, Niamh, and Stout, James R. (2021). “API Continuous Cooling and Antisolvent Crystallization for Kinetic Impurity Rejection in cGMP Manufacturing.” Second Commercializing Flow Chemistry Summit, Virtual Conference, August 26, 2021.
• Mitchell, N., Burcham, C. L., Calado, F., and Myers, S. (2021). “Achieving particle size and impurity control for a continuous crystallization and wet milling process using a digital design approach.” 21st International Symposium on Industrial Crystallization (ISIC21), Virtual, August 30 to September 2, 2021.
• Johnson, Martin D., Burcham, Christopher L., May, Scott A., Calvin, Joel R., McClary-Groh, Jenifer, Myers, Steven S., Webster, Luke P., Roberts, Jeffrey C., Reddy, V. Ramana, Luciani, Carla V., Corrigan,, Aoife P., Spencer, Richard D., Moylan, Robert, Boyse, Raymond, Murphy, John D., Brody, Niamh, and Stout, James R. (2021). “Regulatory Aspects of a cGMP Continuous Drug Substance Process, and Contrasts with Continuous Drug Product” CFRT 2021; Continuous Flow Reactor Technology and Industrial Applications, Virtual Conference, September 15, 2021.
• Burcham, Christopher L. (2021). “Examples of Particle Engineering to Improve Patient Outcomes and Product Manufacturing.” Pharmaceutical Crystallization Summit: Breaking Drug Product Development Bottlenecks via Enabling Technologies Princeton, NJ, October 14 – 15, 2021.
• Burcham, Christopher L. (2021). “Industry vs. Academia & the Importance of Diverse Thought and Inclusivity in Industry.” Annual Biomedical Research Conference for Minority Students (ABRCMS) 2021 Virtual, November 10-13.
• Jonuzaj, S., Burcham, C.L., Galindo, A., Jackson, G., and Adjiman, C. (2021). “A model-based approach to identify optimal formulations for the spray drying of pharmaceutical compounds.” American Institute of Chemical Engineers Annual Meeting, Boston, MA, November 7-11, 2021.
• Jonuzaj, S., Burcham, C.L., Galindo, A., Jackson, G., and Adjiman, C. (2022). “Optimizing the selection of drug-polymer-solvent formulations for spray-dried solid dispersions in pharmaceutical manufacturing.” The 14th International Symposium on Process Systems Engineering, PSE2021+, June 19-23, 2022, Kyoto, Japan.
• Burcham, Christopher L. (2021). “Developing a Continuous Crystallization Processes for an Active Pharmaceutical Ingredient.” University of Strathclyde, Invited Lecture CMAC Seminar Series, Glasgow, Scotland, August 17, 2022.
• Boyle, Christopher, Brown, Cameron, Sefcick, Jan, Burcham, Christopher, Nazemifard, Neda, Perciballi, Francesca, Svoboda, Vaclav, Uyttersprot, Jan-Sebastiaan, and Cardona, Javier, (2022). “Evaluation of Deep Learning methods for particle characterization from in-line imaging and chord length distribution measurements.” Advances in Process Analytics and Control Technologies Conference (APACT 22), Madrid, Spain, September 14-16, 2022.
• Boyle, Christopher, Brown, Cameron, Sefcick, Jan, Burcham, Christopher, Nazemifard, Neda, Perciballi, Francesca, Svoboda, Vaclav, Uyttersprot, Jan-Sebastiaan, and Cardona, Javier, (2022). “Evaluation of Deep Learning methods for particle characterisation from in-line imaging and chord length distribution measurements.” 9th World Congress on Particle Technology (WCPT9), Madrid, Spain, September 18-22, 2022.
• Burcham, C. L., Polster, C., Girard, K. and Mitchell, N. A. (2022) “Scale-up and Optimization of Filtration Processes: Pressure Filter to Centrifuge.” 13th World Filtration Congress, San Diego, CA, Oct. 5 -9, 2022.
• Burcham, C. L., Svoboda, V., Myers, S., Groh, J., Johnson, M. D., Merritt, J. M., Stout, J., Pereira, S., Calado, F., and Mitchell, N. (2022). “Moving the Attainable Region of a Continuous Crystallization Process.” Invited Speaker, Association of Crystallization Technology, 24th Larson Conference, Halifax, Nova Scotia, Canada, October 2 to October 5, 2022.
• Johnson, Martin D., Burcham, Christopher L., May, Scott A., Calvin, Joel R., McClary-Groh, Jenifer, Myers, Steven S., Webster, Luke P., Roberts, Jeffrey C., Luciani, Carla V., Corrigan, Aoife P., Spencer, Richard D., Moylan, Robert, Boyse, Raymond, Murphy, John D., and Stout, James R. (2022). “cGMP Manufacturing Aspects of API Continuous Cooling and Antisolvent Crystallization for Kinetic Impurity Rejection.” 3rd Commercializing Flow Chemistry Summit, Boston, MA, October 13, 2022.
• Johnson, Martin D., Burcham, Christopher L., May, Scott A., Calvin, Joel R., McClary-Groh, Jenifer, Myers, Steven S., Webster, Luke P., Roberts, Jeffrey C., Luciani, Carla V., Corrigan, Aoife P., Spencer, Richard D., Moylan, Robert, Boyse, Raymond, Murphy, John D., and Stout, James R. (2022). “API Continuous Cooling and Antisolvent Crystallization for Kinetic Impurity Rejection in cGMP Manufacturing.” SK Pharmteco Process Development Symposium, Boston, MA, October 13, 2022.
• Burcham, C. L. (2022). “Pharmaceutical Process Development.” Invited Lecturer, Purdue University Dept. of Chemical Engineering (ChE 55100), Lafayette, IN, November 3rd, 2022.
• Burcham, Christopher L. and Wittenberg, Kathryn (2022). “Industry vs. Academia & the Importance of Diverse Thought and Inclusivity in Industry.” Annual Biomedical Research Conference for Minority Students (ABRCMS) 2022, Anaheim, California, November 9-12.
• Boyle, Christopher, Brown, Cameron, Sefcick, Jan, Burcham, Christopher, Nazemifard, Neda, Perciballi, Francesca, Svoboda, Vaclav, Uyttersprot, Jan-Sebastiaan, and Cardona, Javier, (2022). “Quantitative appraisal of analytical techniques for in-line PAT and comparison of deep learning and white-box methods.” American Institute of Chemical Engineers Annual Meeting, Phoenix, AZ, November 13-18, 2022.
• Jonuzaj, S., Malak, W., Burcham, C.L., Galindo, A., Jackson, G., and Adjiman, C. (2022). “An optimization-based approach to identify thermodynamically stable blends for spray drying dispersions.” American Institute of Chemical Engineers Annual Meeting, Phoenix, AZ, November 13-18, 2022.
• Burcham, C. L. (2023). “Industrial Panel.” Invited Speaker, Georgia Institute of Technology, Atlanta, GA, February 28th, 2023.
• Kaczorowski, N., Jonuzaj, S., Miller, R.D., Polster, C., Day, J., Veltri, L., Held, C.B., Reizman, B.J., Burcham, C.L., and Cole, K.P. (2023). “Process development and optimization for the continuous synthesis and workup of active pharmaceutical ingredients.” American Chemical Society Annual Meeting, Indianapolis, IN, March 27-31, 2023.
• Johnson, Martin D., Burcham, Christopher L., May, Scott A., Calvin, Joel R., McClary-Groh, Jenifer, Myers, Steven S., Webster, Luke P., Roberts, Jeffrey C., Reddy, V. Ramana, Luciani, Carla V., Corrigan,, Aoife P., Spencer, Richard D., Moylan, Robert, Boyse, Raymond, Murphy, John D., Brody, Niamh, and Stout, James R. (2023). “Regulatory Aspects of a cGMP Continuous Drug Substance Process, and Contrasts with Continuous Drug Product.” 2023 ISPE; Facilities of the Future Conference, Bethesda, MD, January 31st – February 1st, 2023.
• Burcham, C. L. (2023). “Crystallization Process Development in Pharmaceutical Product Development.” Invited Speaker, Purdue University, West Lafayette, IN, March 2nd, 7th and April, 25th, 2023.
• Johnson, Martin D., Burcham, Christopher L., May, Scott A., Calvin, Joel R., McClary-Groh, Jenifer, Myers, Steven S., Webster, Luke P., Roberts, Jeffrey C., Reddy, V. Ramana, Luciani, Carla V., Corrigan,, Aoife P., Spencer, Richard D., Moylan, Robert, Boyse, Raymond, Murphy, John D., Brody, Niamh, and Stout, James R. (2023). “Regulatory Aspects of a cGMP Continuous Drug Substance Process, and Contrasts with Continuous Drug Product.” University Seminar, March 27th, 2023.
• Burcham, C. L. (2023). “Developing a Continuous Crystallization Processes for an Active Pharmaceutical Ingredient.” Invited Speaker, Strathclyde University, Glasgow, UK, May 5th, 2023.
• Boyle, Christopher, Brown, Cameron, Sefcick, Jan, Burcham, Christopher, Nazemifard, Neda, Calderon de Anda, Jorge, Svoboda, Vaclav, Uyttersprot, Jan-Sebastiaan, and Cardona, Javier, (2023). “Evaluation of methods for particle characterisation from in-line imaging and chord length distribution measurements.” Centre for Process Analytics and Control Technology Webinar, University of Strathclyde, Glasgow, UK, June 1st, 2023.
• McKechnie, David, Burcham, Christopher L., Carasquillo, Ronald, Cousen, Alexander, Douieb, Sélim, Thorat, Alpana A., Brown, Cameron, Siddique, Humera, and Sefcik, Jan (2023). “Development of Continuous Nucleators.” CMAC Summer School 2023, University of Strathclyde, Glasgow, UK, June 15th, 2023.
• McKechnie, David, Burcham, Christopher L., Carasquillo, Ronald, Cousen, Alexander, Douieb, Sélim, Girard, Kevin P., Thorat, Alpana A., Brown, Cameron, Siddique, Humera, and Sefcik, Jan (2023). “Development of Continuous Nucleators.” International Symposium of Industrial Crystallisation (ISIC) 2023, Glasgow, UK, September 5-8, 2023.
• Boyle, Christopher, Sefcick, Jan, Brown, Cameron, Nazemifard, Neda, Burcham, Christopher, Uyttersprot, Jan-Sebastiaan, Calderon de Anda, Jorge, Svoboda, Vaclav, and Cardona, Javier, (2023). “Multidimensional Particle Characterisation from In-Situ Sensors.” International Symposium of Industrial Crystallisation (ISIC) 2023, Glasgow, UK, September 5-8, 2023.
• Kaczorowski, N., Jonuzaj, S., Day, J., Miller, R.D., Veltri, L., Held, C.B., Cole, K.P. and Burcham, C.L. (2023). “Development of a Cryogenic Flow Synthesis and Continuous Extraction Process with Enhanced Yield, Process Control, and Greenness.” 4th CFC Summit 2023 Commercializing Flow Chemistry, Boston, MA, October 16-18, 2023.
• Kaczorowski, N., Jonuzaj, S., Miller, R.D., Polster, C., Day, J., Veltri, L., Held, C.B., Reizman, B.J., Burcham, C.L., and Cole, K.P. (2023). “Development of a cryogenic flow synthesis and continuous counter-current extraction process to manufacture high quality DS with enhanced yield, process control, and greenness.” American Institute of Chemical Engineers Annual Meeting, Orlando, FL, November 5-10, 2023.
• Jonuzaj, S., Kaczorowski, N., Miller, R.D., Polster, C., Day, J., Veltri, L., Held, C.B., Reizman, B.J., Burcham, C.L., and Cole, K.P. (2023). “Digital design and optimization of a continuous counter-current extraction process for purifying active pharmaceutical ingredients.” American Institute of Chemical Engineers Annual Meeting, Orlando, FL, November 5-10, 2023.
• Sefick, Jan, Price, Chris, Lindsay, David, Kerr, William J., Li, Jun, Adjiman, Claire, Calindo, Amparo, Jackson, George, Burcham, Christopher L., Kolis, Stanley P., Donnelly, Liam and Brown, Scott A. (2023). “Introduction to SolvIT: Computer aided and experimentally verified solvent design strategies for sustainable pharmaceutical manufacturing.” CMAC Open Day, Glasgow, UK, November 14-16, 2023.
• Jonuzaj, S., Kaczorowski, N., Miller, R.D., Day, J., Reizman, B.J., Burcham, C.L., and Cole, K.P. (2024). “Continuous synthesis and workup for drug substance manufacturing: A hybrid modelling and experimental design.” IFPAC® - 2024, Bethesda, MD, March 3-6, 2024.
• Bellinghausen, Stefan, Li, Xin, Wang, Lok Hong, Abdullahi, Hassan, Jonuzaj, Suela, Harris, Patrick and Burcham, Christopher (2024). “Development and Application of a MULTI-Component MODEL with Radially Dependent Droplet Drying for Pharmaceutical Spray Drying.” APV Continuous Manufacturing, Mölndal, Sweden, April 23-24, 2024.
• Burcham, Christopher, Cheng, Si, Feist, Rebekah, Kramer, John, Lynch, Matthew, and Patel, Asmita (2024). “Industrial Panel Discussion.” Invited Speaker, University of California Santa Barbara, Santa Barbara, CA, September 19th, 2024.
• Jonuzaj, Suela, Burcham, Christopher, Copeland-Jones, Erin, Fischer, Kerri, Francisco, Paulo, Niemoller, Lexie and Wolfe, Chad (2024). “Defining Suitable Process Operating Range for a Spray Dried Dispersion Using Combined Mechanistic and Statistical Modelling Tools.” American Institute of Chemical Engineers Annual Meeting, San Diego, CA, October 27-31, 2024.
• Harris, Patrick, Jonuzaj, Suela, Bellinghausen, Stefan, Li, Xin, Wang, Lok Hong, Abdullahi, Hassan, Patil, Yogesh, Rose, John and Burcham, Christopher (2024). “Selecting the Appropriate Digital Solution for Pharmaceutical Spray Drying.” American Institute of Chemical Engineers Annual Meeting, San Diego, CA, October 27-31, 2024.
• Mills, Shelby, Muir, Victoria, Ritchie, Stephen and Burcham, Christopher (2024). “How to Leverage Mentorship and Sponsorship to Elevate Your Career.” Invited Panel Discussion, American Institute of Chemical Engineers Annual Meeting, San Diego, CA, October 27-31, 2024.
• Alhasson, Dana, Kao, Peng-Kai and Burcham, Christopher (2024). “Chemical Engineering in the Pharmaceutical Industry.” Panel Discussion, American Institute of Chemical Engineers Annual Meeting, San Diego, CA, October 27-31, 2024.
• Burcham, C. L. (2024). “Application of Quality by Design in the Process Development of Pharmaceuticals.” Invited Speaker, Purdue University, West Lafayette, IN, November 21st, 2024.
• Harris, Patrick, Jonuzaj, Suela, Bellinghausen, Stefan, Li, Xin, Wang, Lok Hong, Abdullahi, Hassan, Patil, Yogesh, Rose, John, & Burcham, Christopher (2025). “Development and Application of a Multi-Component Model with Radially Dependent Droplet Drying for Pharmaceutical Spray Drying.” Siemens Webinar Series, June 12th, 2025.
• Burcham, C. L. (2025). “After Graduate School: The transition to industry… a twenty-seven year journey.” Invited Speaker, Strathclyde University, Glasgow, UK, June 25, 2025.
• Burcham, Christopher L., Harris, Patrick, Jonuzaj, Suela, Patil, Yogesh P., Rose, John P. (2025). “Utilization of Coupled Heat, Mass, and Population Balance Models to Optimize Spray Drying Processes.” 8th International Conference on Population Balance Modeling (PBM2025), August 11th – 13th, 2025.
• Burcham, C. L. (2025). “Examples of Crystal Engineering in the Pharmaceutical Industry and Opportunities for Further Innovation.” Plenary Speaker, 1st Biennial Welch Crystallization Center Symposium, University of Houston, Houston, TX, September 5th, 2025.
• Fischer, Kerri, Burcham, Christopher L., Copeland Jones, Erin D., Jonuzaj, Suela, Wolfe, Chad, Francisco, Paulo, Almeida, Maria Ines, and Sá Couto, Clara. (2025) “Amorphous Solid Dispersions: Defining Process Operating Range across Multiple Units of Similar Construction.” American Institute of Chemical Engineers Annual Meeting, Boston, MA, November 2-6, 2025.
• Schmithorst, Michael B., Rawal, Saurin Hiren, Kallman, Neil J., Held, Charles B., Merritt, Jeremy M. and Burcham, Christopher L. (2025). “pH-Dependent Impurity Rejection in an Acid-Base Crystallization.” American Institute of Chemical Engineers Annual Meeting, Boston, MA, November 2-6, 2025.
• Burcham, C. L. (2025). “ab initio Modeling in the Development of Pharmaceuticals.” Invited Speaker, Imperial College London, London, UK, September 19th, 2025.
• Burcham, C. L. (2026). “ab initio Modeling in the Development of the Crystallization Processes for Pharmaceuticals.” Invited Speaker, EFCE Conference – Crystallization for Pharmaceutical Applications, online, March 12th, 2026.

Honors

• Eli Lilly and Company, Quality Pinnacle Award, recognizes and applauds individuals who strive for excellence in our global R&D community through exemplary quality improvements to enhance drug discovery and development, 2009.
• Eli Lilly and Company, Lilly Engineering Excellence Award Nomination, 2013, 2014.
• Eli Lilly and Company, Lilly Research Laboratory President's Scientific Recognition Award for the "Development, Commercialization, Registration and Launch of REYVOW", for significant achievements across Lilly Research Labs in Delivery for the Patient, 2020.
• Eli Lilly and Company, Engineering Excellence Award, Lifetime achievement award for recognition to an individual who has demonstrated sustained excellence in engineering throughout their career to make a significant impact on both the business and the engineering discipline, 2020.
• Eli Lilly and Company, Lilly Innovator Award for the "Combined Mechanistic and Statistical Modelling Approach to Design Proven Acceptable Range (PAR) Studies for a Commercial Scale Spray Drying Process", recognizes those who work relentlessly to deliver innovation (big or small) to the patients; who follow the science and take risk to experiment; who team up to overcome barriers to deliver, 2023.
• Eli Lilly and Company, Lilly Innovator Award for the "In silico Design and Optimization of the Spay Drying Process through Combined Process Models and Molecular Dynamic Simulations", recognizes those who work relentlessly to deliver innovation (big or small) to the patients; who follow the science and take risk to experiment; who team up to overcome barriers to deliver, 2024.
• Eli Lilly and Company, Top 100 Lilly Innovator Award for the "Combining in silico and in vitro Design to Enable an Important Clinical Study", recognizes the top 100 scientists who work relentlessly to deliver innovation (big or small) to the patients; who follow the science and take risk to experiment; who team up to overcome barriers to deliver, 2024.
• Pharmaceutical Discovery, Development and Manufacturing Forum (PD2M) Outstanding Contribution to Quality by Design for Drug Substance Award, 2018, recognizes professionals who work to further the QbD initiative within the worldwide pharmaceutical industry. The awards recognize excellence in QbD.
• Elected AIChE Fellow, 2023, recognition of "service to the profession" and "significant professional accomplishment."
• AIChE National Award - Industrial R&D Award, 2024, recognizes individuals or teams working in the industries served by chemical engineers, for innovation that has resulted in the successful commercial development of new products and/or new processes for making useful products.
• Elected to National Academy of Engineers, 2026.

Research Honors

• IChemE Global Awards Finalist – Biopharma Award (2025)

Other Honors

• Tau Beta Pi - National Engineering Honor Society
• Phi Lambda Upsilon - Chemistry Honor Society
• Phi Kappa Phi - Honor Society
• Phi Eta Sigma - Freshman Honor Society
• Golden Key National Honor Society
• Alpha Lambda Delta - National Honor Society for First Year Students
• Dean’s List
• Edmund James Scholar
• Children of Veterans of Foreign Wars Scholarship - four-year full tuition
• Mobil Engineering Scholarship Award, 1991
• Honorable Mention - Department of the Army National Defense Science and Engineering Graduate Fellowship Program, 1992, 1993
• Honorable Mention - National Science Foundation Graduate Fellowship in Engineering, 1992
• The Du Pont Fellowship in Chemical Engineering, 1992 - 1997
• NASA Graduate Student Researcher's Program Fellowship, 1994 - 1997

For More Information

• LinkedIn